Protein name:
Zinc finger protein GLI1 ;
Alternative:
Oncogene GLI ;Glioma-associated oncogene ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with KIF7 (By similarity). Interacts with ZIC1; the interaction enhances transcription activation.
Function:
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
Subcellular Location:
Cytoplasm
Nucleus
Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.
Protein Attributes:
50:
MFNSMTPPPI | SSYGEPCCLR | PLPSQGAPSV | GTEGLSGPPF | CHQANLMSGP |
100:
HSYGPARETN | SCTEGPLFSS | PRSAVKLTKK | RALSISPLSD | ASLDLQTVIR |
150:
TSPSSLVAFI | NSRCTSPGGS | YGHLSIGTMS | PSLGFPAQMN | HQKGPSPSFG |
200:
VQPCGPHDSA | RGGMIPHPQS | RGPFPTCQLK | SELDMLVGKC | REEPLEGDMS |
250:
SPNSTGIQDP | LLGMLDGRED | LEREEKREPE | SVYETDCRWD | GCSQEFDSQE |
300:
QLVHHINSEH | IHGERKEFVC | HWGGCSRELR | PFKAQYMLVV | HMRRHTGEKP |
350:
HKCTFEGCRK | SYSRLENLKT | HLRSHTGEKP | YMCEHEGCSK | AFSNASDRAK |
400:
HQNRTHSNEK | PYVCKLPGCT | KRYTDPSSLR | KHVKTVHGPD | AHVTKRHRGD |
450:
GPLPRAPSIS | TVEPKREREG | GPIREESRLT | VPEGAMKPQP | SPGAQSSCSS |
500:
DHSPAGSAAN | TDSGVEMTGN | AGGSTEDLSS | LDEGPCIAGT | GLSTLRRLEN |
550:
LRLDQLHQLR | PIGTRGLKLP | SLSHTGTTVS | RRVGPPVSLE | RRSSSSSSIS |
600:
SAYTVSRRSS | LASPFPPGSP | PENGASSLPG | LMPAQHYLLR | ARYASARGGG |
650:
TSPTAASSLD | RIGGLPMPPW | RSRAEYPGYN | PNAGVTRRAS | DPAQAADRPA |
700:
PARVQRFKSL | GCVHTPPTVA | GGGQNFDPYL | PTSVYSPQPP | SITENAAMDA |
750:
RGLQEEPEVG | TSMVGSGLNP | YMDFPPTDTL | GYGGPEGAAA | EPYGARGPGS |
800:
LPLGPGPPTN | YGPNPCPQQA | SYPDPTQETW | GEFPSHSGLY | PGPKALGGTY |
850:
SQCPRLEHYG | QVQVKPEQGC | PVGSDSTGLA | PCLNAHPSEG | PPHPQPLFSH |
900:
YPQPSPPQYL | QSGPYTQPPP | DYLPSEPRPC | LDFDSPTHST | GQLKAQLVCN |
950:
YVQSQQELLW | EGGGREDAPA | QEPSYQSPKF | LGGSQVSPSR | AKAPVNTYGP |
1000:
GFGPNLPNHK | SGSYPTPSPC | HENFVVGANR | ASHRAAAPPR | LLPPLPTCYG |
1050:
PLKVGGTNPS | CGHPEVGRLG | GGPALYPPPE | GQVCNPLDSL | DLDNTQLDFV |
1100:
AILDEPQGLS | PPPSHDQRGS | SGHTPPPSGP | PNMAVGNMSV | LLRSLPGETE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Chicken
ELISA Kit for Human Zinc finger protein GLI1
ELISA Kit for Human Zinc finger protein GLI1
ELISA Kit for Human Zinc finger protein GLI1
CLIA Kit for Human Zinc finger protein GLI1
CLIA Kit for Human Zinc finger protein GLI1
CLIA Kit for Human Zinc finger protein GLI1
Polyclonal Antibody for Human Zinc finger protein GLI1
Polyclonal Antibody for Human Zinc finger protein GLI1
Polyclonal Antibody for Human Zinc finger protein GLI1
Monoclonal Antibody for Human Zinc finger protein GLI1
Monoclonal Antibody for Human Zinc finger protein GLI1
Monoclonal Antibody for Human Zinc finger protein GLI1
Protein for Human Zinc finger protein GLI1
Protein for Human Zinc finger protein GLI1
Protein for Human Zinc finger protein GLI1
R&D Technical Data
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Precision
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Recovery
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Linearity
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